THE ROLE OF CERTAIN BLOOD COAGULATION SYSTEM FACTORS IN PREDICTING RECURRENT GASTRODUODENAL ULCER BLEEDING

Abstract

• In the structure of complicated forms of ulcer disease, gastroduodenal hemorrhages (GDK) account for 42-47%. Despite the widespread introduction of H-2 receptor antagonists, proton pump inhibitors, and antihelicobacter therapy, the number of patients with disease recurrences and gastroduodenal bleeding is increasing to 60%, and mortality remains above 10%. Between 20 and 220 out of 100,000 people worldwide suffer from stomach and duodenal ulcers, with an annual mortality rate of 246,000. WHO data 2008 (Button L A 2011, Savelyev V C 2013)..