CLINICAL AND IMMUNOLOGICAL APPROACH TO IMPROVING THE EFFECTIVENESS OF CARDIAC SURGERY IN PATIENTS WITH MYOCARDIAL REPERFUSION DISORDERS

Authors

  • Umarov Bakhtiyor Yatgarovich Автор
  • Siddiqov Azizbek Murod-ugli Автор

DOI:

https://doi.org/10.5281/zenodo.17383631

Abstract

This study evaluates the role of clinical and immunological monitoring in optimizing cardiac surgery outcomes complicated by myocardial reperfusion injury. A total of 122 patients undergoing surgery with cardiopulmonary bypass were analyzed. Serial measurements of IL-6, TNF-α, CRP, Fas/FasL, and Caspase-3 were performed pre- and postoperatively. Elevated cytokine and apoptosis marker levels were associated with prolonged inotropic support, low ejection fraction, and extended ICU stay. Implementation of individualized immunological correction, including anti-inflammatory and antioxidant therapy, reduced postoperative complications by 28%. The integrated clinical–immunological approach demonstrated clear efficacy in improving cardiac function and overall recovery dynamics. 

 

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Published

2025-10-18

Issue

Vol. 1 No. 1 (2025): International Conference on Business & Management

Section

Статьи

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How to Cite

Umarov, B., & Siddiqov, A. (2025). CLINICAL AND IMMUNOLOGICAL APPROACH TO IMPROVING THE EFFECTIVENESS OF CARDIAC SURGERY IN PATIENTS WITH MYOCARDIAL REPERFUSION DISORDERS. International Conference on Business & Management, 1(1), 49-50. https://doi.org/10.5281/zenodo.17383631