DETERMINATION OF OPTIMAL DISSOLUTION TEST CONDITIONS FOR “NAVESTO” CAPSULES

Auteurs

  • F.Kh. Maksudova 1 Автор
  • N.M. Vakhidova 1 Автор
  • Z.B. Bakhtiyorova 1 Автор

Résumé

The therapeutic efficacy of antihypertensive drugs is closely associated with their biopharmaceutical characteristics, particularly the solubility and dissolution behavior of the active pharmaceutical ingredients (APIs). Therefore, the evaluation of in vitro biopharmaceutical performance, including dissolution testing, represents a critical component of pharmaceutical quality assessment. Since the solubility of valsartan and sacubitril is highly dependent on the pH of the dissolution medium, the scientific justification of optimal dissolution test conditions for “Navesto” capsules containing these active ingredients is of particular importance. Establishing appropriate dissolution conditions and evaluating the in vitro biopharmaceutical characteristics of the formulation are essential for ensuring its quality, performance, and potential therapeutic efficacy. 

 

Téléchargements

Publiée

2026-08-01

Numéro

Vol. 2 No 7 (2026)

Rubrique

Articles

Licence

Creative Commons License

Ce travail est disponible sous la licence Creative Commons Attribution 4.0 International .

By submitting a paper to the conference organized by Academic Publishing House, the author(s) agree to the following license terms and conditions:

1. Copyright and Licensing

  1. The author(s) retain the copyright of their article.
  2. The author(s) grant Academic Publishing House a non-exclusive license to publish, distribute, and archive the submitted material in both electronic and print formats.
  3. The work will be published under the Creative Commons Attribution (CC BY 4.0) license, allowing others to share and adapt the material for any purpose, provided proper credit is given to the original author(s).

2. Author’s Responsibilities

  1. The author(s) guarantee that the submitted work is original, does not infringe any existing copyrights, and has not been published or submitted elsewhere.
  2. The author(s) confirm that all co-authors have approved the final version of the manuscript and agree with its submission and publication.
  3. The author(s) are fully responsible for the accuracy of the data, citations, and references provided in the article.

3. Publisher’s Rights

  1. Academic Publishing House reserves the right to edit, format, and make minor grammatical or layout corrections to the paper without altering its core content.
  2. The publisher has the right to include the article in indexing databases, archives, and repositories such as Google Scholar, Zenodo, OpenAIRE, and other partner platforms.
  3. The publisher may promote the paper through its website and official social media channels.

4. Open Access Policy

All conference papers are published as open access, ensuring free and permanent online access to the full text of all articles immediately upon publication.

5. Withdrawal and Retraction

If ethical misconduct, plagiarism, or data manipulation is detected, Academic Publishing House reserves the right to withdraw or retract the publication at any stage.

6. Acceptance of Terms

Submission of a manuscript to the conference implies that the author(s) have read, understood, and accepted these License Terms.

Comment citer

Maksudova, F., Vakhidova, N., & Bakhtiyorova, Z. (2026). DETERMINATION OF OPTIMAL DISSOLUTION TEST CONDITIONS FOR “NAVESTO” CAPSULES . International Conference on Social Sciences & Humanities, 2(7), 67-68. https://uniconflix.com/index.php/ICSH/article/view/5596