THE IMPACT OF RENAL MARKERS IN PARKINSON’S DISEASE

Abstract

This study aims to investigate the relationship between renal and metabolic markers and the progression of Parkinson’s disease (PD). In recent years, increasing evidence has supported the systemic nature of PD, which involves not only neurodegenerative but also metabolic, vascular, and renal changes. The analysis of biochemical parameters makes it possible to detect hidden signs of excretory system dysfunction and to assess their impact on disease progression. The results of this study demonstrate that elevated levels of urea and glucose, as well as reduced hematocrit, correlate with the progression of Parkinson’s disease, reflecting the systemic involvement of peripheral organs in the pathological process. Identifying such alterations has important clinical significance for early diagnosis, prevention of complications, and personalized therapy.