MORPHO-FUNCTIONAL CHANGES OF HEPATIC CELLS UNDER THE INFLUENCE OF FASTOKINE

Abstract

The liver, as the primary metabolic hub of the vertebrate body, exhibits remarkable plasticity in response to systemic signaling molecules. Fastokine, a recently identified peptide hormone predominantly secreted during rapid metabolic transitions, has emerged as a significant modulator of hepatic architecture and function. This article explores the cellular transformations, enzymatic shifts, and structural reorganizations that occur within hepatocytes following chronic and acute exposure to Fastokine. Understanding these morpho-functional changes is critical for assessing the hormone’s potential therapeutic applications in metabolic syndrome and its risks regarding hepatic steatosis.