COMPARATIVE EFFECTIVENESS OF HEMODIALYSIS AND HEMODIAFILTRATION IN THE TREATMENT OF END-STAGE CHRONIC KIDNEY DISEASE

Abstract

End-stage chronic kidney disease (ESKD) represents the final and irreversible stage of renal impairment, requiring renal replacement therapy to sustain life.1 Hemodialysis (HD) remains the most widely used modality worldwide, while hemodiafiltration (HDF) has emerged as an advanced technique offering improved solute clearance and potential survival benefits.2 Despite growing interest, the comparative effectiveness of HD and HDF remains a topic of ongoing clinical investigation.3 This study focuses on evaluating clinical, biochemical, and hemodynamic outcomes in ESKD patients undergoing HD versus HDF