ВЗАИМОСВЯЗЬ КАЧЕСТВЕННОГО СОСТАВА КИШЕЧНОЙ МИКРОБИОТЫ И ПОКАЗАТЕЛЕЙ СИСТЕМНОГО И ЛОКАЛЬНОГО ИММУННОГО СТАТУСА У ДЕТЕЙ РАННЕГО И ДОШКОЛЬНОГО ВОЗРАСТА

Authors

  • Нигинабону Субханова 1 Автор

Abstract

В работе представлены результаты комплексного клинико-лабораторного исследования, посвященного изучению влияния микробиоценоза кишечника на формирование мукозального и системного иммунитета у детей в возрасте от 6 месяцев до 7 лет. Методами ПЦР-РВ и ИФА оценен таксономический состав микробиоты и иммунологический статус (sIgA, цитокины IL-4, IFN-γ). Доказано, что глубокий дефицит индигенной флоры коррелирует со снижением локальной защиты кишечника и поляризацией системного иммунного ответа по Th2-пути. Обоснована необходимость своевременной коррекции дисбиотических нарушений для профилактики иммунопатологических состояний у детей. 

 

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Published

2026-09-12

Issue

Vol. 2 No. 9 (2026)

Section

Статьи

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How to Cite

Субханова, Н. (2026). ВЗАИМОСВЯЗЬ КАЧЕСТВЕННОГО СОСТАВА КИШЕЧНОЙ МИКРОБИОТЫ И ПОКАЗАТЕЛЕЙ СИСТЕМНОГО И ЛОКАЛЬНОГО ИММУННОГО СТАТУСА У ДЕТЕЙ РАННЕГО И ДОШКОЛЬНОГО ВОЗРАСТА . International Conference on Science & Technology, 2(9), 26-28. https://uniconflix.com/index.php/ICST/article/view/5881