ЭПИГЕНЕТИЧЕСКИЕ И МОЛЕКУЛЯРНЫЕ МЕХАНИЗМЫ УСТОЙЧИВОСТИ К ТЕРАПИИ РЕЦИДИВИРУЮЩЕГО ЛАРИНГОТРАХЕИТА У ДЕТЕЙ

Authors

  • Зебо Сафоева Автор

DOI:

https://doi.org/10.5281/zenodo.18580159

Abstract

Рецидивирующий ларинготрахеит (РЛТ) у детей остаётся актуальной проблемой педиатрии и оториноларингологии из-за высокой частоты повторных эпизодов, риска стеноза гортани и недостаточной эффективности стандартной противовоспалительной терапии у части пациентов. Несмотря на широкое применение ингаляционных кортикостероидов, у некоторых детей сохраняется высокая частота рецидивов, что указывает на индивидуальные механизмы терапевтической резистентности. Эпигенетические и молекулярные факторы, включая метилирование ДНК и регуляцию экспрессии микроРНК, способны модулировать воспалительный ответ дыхательных путей и влиять на чувствительность к терапии. 

 

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Published

2026-02-10

Issue

Vol. 2 No. 2 (2026): International Conference on Science & Technology (ICST)

Section

Статьи

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How to Cite

Сафоева, З. (2026). ЭПИГЕНЕТИЧЕСКИЕ И МОЛЕКУЛЯРНЫЕ МЕХАНИЗМЫ УСТОЙЧИВОСТИ К ТЕРАПИИ РЕЦИДИВИРУЮЩЕГО ЛАРИНГОТРАХЕИТА У ДЕТЕЙ. International Conference on Science & Technology, 2(2), 27-28. https://doi.org/10.5281/zenodo.18580159