EVALUATION OF RENAL DYSFUNCTION IN PRE-ECLAMPSIA

Authors

  • Mirzaeva Gulchehra Payzullaevna Автор
  • Jabbarov Ozimbay Otakxanovich Автор

DOI:

https://doi.org/10.5281/zenodo.17312149

Abstract

Pre-eclampsia (PE) is a hypertensive disorder unique to pregnancy, characterized by systemic endothelial dysfunction leading to multi-organ involvement. Among the affected organs, the kidneys play a pivotal role both in the pathogenesis and in clinical manifestations. This review discusses the mechanisms of renal dysfunction in pre-eclampsia, current diagnostic methods including biochemical and Doppler parameters, and their clinical significance in evaluating disease severity and predicting outcomes. Understanding renal changes in pre-eclampsia aids in early detection, improved monitoring, and prevention of complications for both mother and fetus.. 

 

References

1.Козловская Н.Л., Меркушева Л.И., Кирсанова Т.В. и др. Влияние дисбаланса плацентарных факторов ангиогенеза на клинические проявления «ранней» и «своевременной» преэклампсии. Нефрология и диализ 2013; 15(3): 206–215

2.Козловская Н.Л., Меркушева Л.И., Кирсанова Т.В. и др. Дисбаланс плацентарных факторов ангиогенеза и клинические особенности «ранней» и «своевременной» преэклампсии. Взгляд нефролога. Архив акушерства и гинекологии им. В.Ф.Снегирева 2014; 1:13–21

3.Тареева ИЕ. Нефрология: Руководство для врачей. Медицина, М., 2000; 464–473

4.Baumwell S, Karumanchi SA. Pre-eclampsia: clinical manifestation and molecular mechanisms. Nephron Clin Pract 2007;106:72–81. doi.org/10.1159/000101801

5.Bollee, G, Patey N, Cazajous G et al. Thrombotic microangiopathy secondary to VEGF pathway inhibition by sunitinib. Nephrol Dial Transplant 2008; 24: 682–685. doi.org/10.1093/ndt/gfn657

6.Cohen AW, Burton NG. Nephrotic syndrome due to preeclamptic nephropathy in hydatidiform mole and coexistent fetus. Obstet Gynaecol 1979; 53: 130–134

7.Davison JM, Dunlop W. Renal hemodynamics and tubular function normal human pregnancy. Kidney Int 1980; 18: 152–161. doi.org/10.1038/ki.1980.124

8.Duley L. The global impact of pre-eclampsia and eclampsia. Seminars in Perinatology 2009;33(3):130–137. doi.org/10.1053/j.semperi.2009.02.010

9.Eremina V, Jefferson A, Kowalewska J et al. VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med 2008; 358: 1129–1139. doi.org/10.1056/NEJMoa0707330

10.Henao DE, Mathieson PW, Saleem MA et al. A novel renal perspective of preeclamsia: a look from the podocyte. Nephrol Dial Transplant 2007;22(5): 1477.doi:10.1093/ndt/gf1804

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Published

2025-10-10

Issue

Vol. 1 No. 1 (2025): International Conference on Science, Education & Law

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Articles

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How to Cite

Mirzaeva, G., & Jabbarov, O. (2025). EVALUATION OF RENAL DYSFUNCTION IN PRE-ECLAMPSIA. International Conference on Science, Education & Law, 1(1), 80-81. https://doi.org/10.5281/zenodo.17312149