EVALUATION OF CHEMOTHERAPY EFFECTIVENESS IN GLIOBLASTOMA ACCORDING TO MOLECULAR-GENETIC TYPE

Abstract

Glioblastomas are characterized by high aggressiveness, rapid recurrence, and short survival duration [2,3]. Determining molecular-genetic characteristics plays an important role in selecting an individualized treatment strategy, particularly in predicting response to temozolomide-based chemotherapy [1,4]. In this study, the impact of molecular markers on chemotherapy effectiveness, overall survival, and progression-free survival was evaluated using clinical and statistical analysis..